Discovery of a new substance in plants to reduce human obesity

Discovery of a new substance in plants to reduce human obesity
Hong Kong: Chinese scientists studying obesity have discovered a substance in plants that can help us reduce obesity.

Scientists have known for years that the natural process of dissolving fat (fat metabolism) in obese people is affected and slowed down, which not only increases their obesity but also makes it very difficult for them to reduce obesity.

The root of the problem lies in the mitochondria, also called cellular powerhouses, because they break down the food molecules inside the cells to produce the energy that many of us need. C is used to meet physical needs.
In healthy people the mitochondria work perfectly, but in obese people it is difficult to break down fat molecules and thus obesity increases once it starts.

In this regard, a protein called “BDNF” has also been discovered. By the way, it is related to the repair of nerve cells, but recent research has found that it also helps mitochondria to break down fat molecules and produce energy.

Obese people make very small amounts of this protein and as a result they become more obese.

Dr. Chi Bun Chan and his colleagues at the University of Hong Kong continued their research by focusing on a substance called “7,8-dihydroxyfluvone” which is similar to BDNF. Burns and is found naturally in a South American plant.

Clinical trials of the substance are ongoing in the treatment of Alzheimer’s, and in experiments on mice it has been shown to restore mitochondrial function.

In the new experiments, Dr. Chi and his colleagues tested “7,8-di-hydroxy flavonoids” placed in a petri dish on human muscle cells that had been affected by mitochondria.

They found that “7,8-di-hydroxy flavonoids” helped mitochondria to break down fats in exactly the same way as BDNF does.

The experiments were then repeated on mice that were obese through genetic modification, which showed that the use of “7,8-dihydroxy flavonoids” reduced their fat content.

So can a new drug to reduce obesity be developed from “7,8-dihydroxy flavonoids”? Dr. Chi Bun Chan hopes that can happen.

However, this discovery is the first step in that direction. In the next phase, it will be tested on other animals, and if successful, human clinical trials will begin.

If all these steps are taken successfully, then it is very possible that a new, unique and effective medicine for obesity will be available in the next eight to ten years.

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